丁丙氢化可的松霜膏治疗皮炎湿疹类皮肤病的疗效

The clinical efficacy of hydrocortisone buteprate cream in treatment of dermatitis and eczema

目的:评价丁丙氢化可的松霜膏治疗皮炎湿疹类皮肤病的疗效和安全性。方法:采用随机对照开放试验,试验组188例,用丁丙氢化可的松霜膏涂于患处,tid,对照组120例用丁酸氢化可的松(尤卓尔)霜涂于患处,tid,疗程3～25d。结果:试验组的临床有效率、痊愈率及不良反应率分别为93.6％,77.7％和7.4％,对照组分别为92.5％,75.0％和8.4％,2组疗效和安全性结果经统计学处理均无显著性差异(P>0.05)。结论:丁丙氢化可的松霜膏治疗皮炎湿疹类皮肤病具有较好临床疗效。

Objective:To observe the efficacy and safety of hydrocortisone buteprate cream (Pan-del) intreatment of dermatits and eczema. Methods: The randomized, controlled, open trial was conducted in 308 patients with dermatitis or eczema. They were divided to receive enternal application of Pandel tid for 3-25d (n = 188) or hydrocortisone butyrate cream tid for 3-25d. Results: The effective rate, cure rate, and incidence of adverse reaction for Pandel group were 93.6% ,77.7% , and 7.4% respectively,and for hydrocortisone butyrate cream group were 92.5% ,75.0% and 8.4% respectively . No significant difference was observed between groups in efficacy and safety (P > 0. 05). Conclusion :Hydrocortisone buteprate cream is effective in treatment of dermatitis and eczema.