双室起搏治疗充血性心力衰竭近期疗效研究

Short-term Effectiveness of Biventricular Pacing Therapy in Patients With Congestive Heart Failure

为进一步观察双室起搏对充血性心力衰竭 (简称心衰 )治疗的效果 ,对 10例充血性心衰病人置入InSync(三腔 )起搏器 ,并观察术前及术后 3个月临床症状及心功能指标的情况。结果 :置入起搏器术后 3个月 ,心功能明显改善 ,从 3.4 4± 0 .5 2级降至 1.5 0± 0 .72级 (P <0 .0 1) ,心衰症状评分从 8.1± 3.2 9分降至 1.4± 1.74分 (P <0 .0 1) ,左室舒张末期内径从 6 7± 6 .6 8mm减至 6 2 .75± 5 .92mm(P <0 .0 5 ) ,射血分数从 0 .35± 0 .0 7增至 0 .4 3± 0 .10 (P <0 .0 5 )。结论 :双室起搏治疗可明显改善心功能 ,提高病人生活质量 ,逆转左室重塑。

In order to study the 3-month follow up effectiveness of biventricular pacing therapy in patients with congestive heart failure,ten patients with congestive heart failure received biventricular pacemaker. At baseline parameters were evaluated:clinical symptoms and heart function. Results: Heart failure in New York Heart Association (NYHA) functional class decreased from 3.44±0.52 to 1.50±0.72 ( P <0.01). Crackles heart failure symptoms score decreased from 8.1±3.29 to 1.4±1.74 ( P <0.01). Left ventricular end-diastolic dimension decreased from 67.00±6.68 mm to 62.75±5.92 mm ( P <0.05) . Left ventricular ejection fraction increased from 0.35±0.07 to 0.43±0.10 ( P <0.05). Conclusion:Biventricular pacing could improve heart function,quality of life and reversal left ventricular remodeling.