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足突裂孔隔膜相关蛋白分子研究进展

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摘要 肾小球足细胞的足突裂孔隔膜是肾小球滤过屏障的重要结构 ,其特异的结构及功能蛋白分子是维持肾小球滤过屏障功能的基础 ,已获得的裂孔隔膜相关蛋白的信息资料增进了对足细胞及其足突裂孔隔膜生物学作用的认识 ,有利于进一步揭示蛋白尿的发生机制 ,为肾脏病基础与临床研究开辟了新的广阔的前景。
出处 《国外医学(生理病理科学与临床分册)》 2003年第6期604-607,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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  • 1Mundel P, Shankland SJ. Podocyte biology and response to injury[J]. J Am Soc Nephrol, 2002,13(12) :3005-3015.
  • 2Kestila M, Ienkkeri U, Mannikko M, et al. Positionally cloned gene for a novel glomerula protein-nephrin-is mutated incongenital nephrotic syndrome[J]. Mol Cell, 1998, 1: 575-82.
  • 3Kaplan, Joshua. Pollak, Martin R. Familial focal segmental glomerulosclerosis[J]. Cur Opin Nephron & Hypertension, 2001,10(2) :183-187.
  • 4Ruotsalainen V, Patrakka J, Tissari P, et al. Role of nephrin in cell junction formation in human nephrogenesis [J]. Am J Pathol.2000,157(6): 1905-1916.
  • 5Putaala H, Soininen R, Kilpelainen P, et al. The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to nassive proteinuria and neonatal death[J]. Hum Mol Genet. 2001, 10(1): 1-8.
  • 6Huber TB, Kottgen M, Schilling B, et al. Interaction with podocin facilitates nephrin signaling[ J ]. J Biol Chem, 2001,276: 41543-41546.
  • 7Sellin L, Huber TB, Gerke P, et al. NEPHl defines a novel fanily of podocin interacting proteins[ J]. FASEB J, 2003, 17 ( 1 ) :115-117.
  • 8Huber TB, Schmidts M, Gerke P, et al. The carboxyl terminus of neph family members binds to the PDZ domain protein zonula occludens-1 [ J]. J Biol Chem,2003,278:13417-13421.
  • 9Gerke P, Huber TB, Sellin L, et al. Homodimerization and Heterodimerization of the Glomerular Podocyte Proteins Nephrin and NEPHl [J]. J Am Soc Nephrol,2003, 14(4) :918-926.
  • 10Ihalmo P, Palmen T, Ahola H,et al. Filtrin is a novel member of nephrin-like proteins. Biochemical & Biophysical Research Communications, 2003, 300(2) :364-370.

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