糖尿病患者PAI-1异常的发生机制及其治疗对策被引量：2

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摘要糖尿病患者由于高血糖、高甘油三酯及高胰岛素血症等因素的存在 ,往往有血浆PAI 1水平升高、纤溶活性下降 ,这是造成高凝状态的重要因素之一。通过饮食调整、运动以减轻体重 ,口服双胍类、噻唑烷二酮类、调脂药及血管紧张素转化酶抑制剂 (ACEI)等药物的治疗 ,可以有效地降低PAI 1水平 ,从而减少心脑血管并发症的发生与发展。

作者唐伟沈备刘超

机构地区南京医科大学第一附属医院内分泌科

出处《国外医学（生理病理科学与临床分册）》 2003年第6期636-638,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)

关键词糖尿病血浆纤溶酶原激活物抑制剂-1 高胰岛素血症

分类号 R587.1 [医药卫生—内分泌]

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