基因组学与肿瘤的筛检被引量：1

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摘要生物医学已进入后基因组时代。随着基因组学技术的日趋完善 ,基因标志物及相应的检测方法已逐步成为肿瘤早期诊断和风险评价的可靠依据 ,并在肿瘤的筛检工作中发挥重要的作用。

作者贺舜王贵齐

机构地区中国医学科学院肿瘤医院内镜科

出处《国外医学（生理病理科学与临床分册）》 2003年第6期561-563,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)

基金卫生部部属 (管 )医院临床学科重点项目 ([2 0 0 1] 3 2 1)

关键词基因组学筛检肿瘤标志物

分类号 R730.49 [医药卫生—肿瘤]

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1Pollak MN, Foulkes WD. Challenges to cancer control by screening[ J ]. Nat Rev Cancer, 2003,3 ( 4 ) :297-303.
2Smith RA, Cokkinides V, Eyre HJ. American cancer society guidelines for the early detection of cancer, 2003 [ J ]. CA Cancer J Clin,2003, 53(1) :27-43.
3Alaiya AA, Franzen B, Auer G, et al . Cancer preoteomics:From identification of novel markers to creation of artifical learning models for tumor classification [ J ]. Electrophoresis, 2000, 21 ( 6 ): 1210.
4Laird PW. The power and the promise of DNA methylation markers[J]. Nat Rev Cancer, 2003, 3(4) :253-266.
5Inai M, Kano M, Shimada Y, Telomerase activity of the Lugolstained and -unstained squamous epithelia in the process of oesophageal carcinogenesis[ J ]. Br J Cancer,2001,85 (7): 1006-1013.
6Parrella P, Xiao Y, Fliss M, et al . Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspiratesl[J]. Cancer Res, 2001,61(20) :7623-7626.
7Kram A, Li L, Zhang RD, et al . Mapping and genome sequence analysis of chromosome 5 regions involved in bladder cancer progression[J]. Lab Invest, 2001 , 81 (7) :1039-1048.
8Yoon DS, Li L, Zhang RD, et al . Genetic mapping and DNA sequence-based analysis of deleted regions on chromosome 16 involved in progression of bladder cancer from occult preneoplastic conditions to invasive disease [ J ]. Oncogene, 2001,20 (36) :5005 - 5014.
9Mori Y, Yin J, Rashid A, et al. Instabilotyping: Comprehensive identification of frameshift mutations caused by coding region microsatellite instability[ J]. Cancer Res,2001,61 (16) :6046-6049.
10Maitrat A, Wistuba LL, Washinton C, et al . High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss [ J ]. Am J Pathol,2001,159 ( 1 ): 119-130.

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1黄德寅,刘琦,王卉,龙翔云.尿脱落细胞检查在联苯胺作业工人健康监护中的作用[J].职业卫生与应急救援,2004,22(2):59-60. 被引量：1
2葛宪民,陈晓琴,陈婷婷,苏素花,翟日洪,周少诗,甘永金.铅镉铝砷苯及X射线致淋巴细胞染色单体互换畸变的特性研究[J].广西医科大学学报,2004,21(4):472-475. 被引量：2
3龙耀庭.生物大分子（DNA及蛋白质）加和物的质谱分析鉴别[J].环境科学,1995,16(6):79-82. 被引量：3
4Lee A J, Hodges N J, Chipman J K. Interindividual variability in response to sodium dichromate-induced oxidative DNA damage: role of the S, er326Cys polymorphism in the DNA-repair protein of 8-oxo- 7, 8-dihydro-2'-deoxyguanosine DNA glycosylase 1 [ J ]. Cancer Epidemiol Biomarkers Prey, 2005, 14: 497-505.
5Setlow R B. Variations in DNA repair among humans//Harris CC, Autrp HN, ed, Human carcinogenesis[M]. New York: Academic Press, 1983: 231-254.
6Pavanello Sofia, Pulliero Alessandra, Siwinska Ewa, et al. Reduced nucleotide excision repair and GSTM1-null genotypes influence anti-B[a] PDE-DNA adduct levels in mononuclear white blood cells of highly PAH-exposed coke-oven workers [ J ]. Carcinogenesis, 2005, 26 (1): 169-175.
7Bodell W J, Levay G, Pongracz K. Investigation of benzene DNA adducts and their detection in human bone marrow [ J ]. Environ Health Perspect, 1993, 99: 241-244.
8Paul W, Brandt-Rauf. New Markers for monitoring occupational cancer: The example of oncogene [ J ]. Journal of Occupational Medicine, 1998, 30 (5): 399.
9Harem R D. Occupational cancer in the oncogene era [J]. Brit Industr Med, 1990, 47: 217.
10Barbone F, Bovenzi M, Cavalliei F, et al. Cigarette smoking and histolog~ctype of lung cancer in men [J]. Chest, 1997, 112 (6) : 1474-1479.