摘要
From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca 2+ antagonistic activity.
From the roots of Panax notoginseng fourteen cyclodipeptides 1-14 were isolated including one new compound (1),seven new natural compounds (4-10) and six known compounds (2-3,11-14) together with one known other compound 15.The chemical structure of 1 was elucidated as cyclo-(Leu-Thr) based on spectral methods.From the roots of Panax ginseng five known lactams (16-20) including pyroglutamic acid were isolated together with butyric diacid,daucosterol and sucrose.The primary bioactivity test showed that pyroglutamic acid and its n-butyl derivative have weak Ca 2+ antagonistic activity.
出处
《云南植物研究》
CSCD
北大核心
2003年第3期366-368,共3页
Acta Botanica Yunnanica
基金
ThisworkwassupportedbygrantsfromtheNationalNaturalScienceFundationofChina (395 0 0 182 )andNatu ralScienceFundofYunnanProvince (95C0 88Q)
关键词
三七
人参
五加科
环二肽
内酰胺
Panax notoginseng
Panax ginseng
Araliaceae
cyclodipeptides
lactams
