SARS 45例临床分析

Clinical analysis of 45 patients with Severe Acute Respiratory Syndrome

目的 :探讨严重急性呼吸道综合征 (SevereAcuteRespiratorySyndrome ,SARS ,即非典型肺炎 )的临床及放射学特点。方法 :通过分析我院 2 0 0 3年 4月 5日至 4月 2 0日收治的 4 5例SARS患者的临床表现、胸片特点、病情发展过程及重症肺炎情况 ,总结SARS的发病特点及发展规律。结果 :SARS传染性强 ,造成群体短期集中发病 ;以发热为首要表现 ,发热均在 38.5℃以上 ;白细胞正常或偏低 ;先发热后有胸片变化 ,近 80 %的患者在起病 2 4h后出现胸片异常 ;71.1%患者间隔 4 8h胸片有进展。 2 4 .4 %的患者进展为重症肺炎。结论 :SARS是传染性很强的疾病 ,有一定的临床及放射学特点 ,病情有进行性加重趋势 ;早发现、早隔离、早治疗是避免疫情播散。

Objective: To explore the clinical and radiology features of Severe Acute Respiratory Syndrome (SARS). Methods: Analysis the clinical presentations, chest radiographs, courses of disease and the features of severe pneumonia of 45 cases with SARS diagnosed between April 5 and April 20, 2003 in our hospital. Results: SARS appears to has high infectivity, and cause of the outbreak. The most common symptom is fever (in 100 percent of the patients). The count of leukocyte is normal or decrease (leukopenia). 80 percent of SARS patients became fever for 24 hours and then have abnormal chest radiographs, serial chest radiographs showed progression of pulmonary infiltrates within 48 hours in 71.1 percent of patients. The percent of severe pneumonia (24.4%) is higher than typical pneumonia. Conclusion: SARS is a disease with high infectivity, and has its own clinical and radiology features. Early recognition, prompt isolation, and appropriate therapy are the key in combating this infection.