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丁香多总皂对HBV转染细胞表达功能的影响 被引量:4

Effects of the extract of Syringa on the secretions of HBsAg and HBeAg in HepG2.2.15 cells
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摘要 目的 :观察丁香多总皂对HepG2 .2 .15细胞分泌HBeAg和HBsAg的影响 .方法 :采用酶联免疫吸附 (ELISA)法检测培养上清中HBeAg和HBsAg表达的变化并以抑制率来表示 .结果 :丁香多总皂对HBeAg和HBsAg的分泌具有抑制作用 ,该作用呈现剂量依赖性和时间依赖性 .结论 AIM: To observe the effects of the extract of Syringa on the secretions of HBsAg and HBeAg in HepG 2.2.15 cells. METHODS: Enzyme linked immunosorbent assay (ELISA) was used to detect the secretions of HBsAg and HBeAg and the suppressive rate was used to represent the values. RESULTS: The extract of Syringa suppressed the secretions of HBsAg and HBeAg in a dose dependent and time dependent manner. CONCLUSION: The suppressive effects of the extract of Syringa on the secretions of HBsAg and HBeAg suggest that the extract of Syringa has some effects of anti hepatitis B viruses in vitro .
出处 《第四军医大学学报》 CAS 北大核心 2003年第13期1234-1235,共2页 Journal of the Fourth Military Medical University
关键词 丁香多总皂 肝炎E抗原 乙型肝炎 表面抗原 HEPG2.2.15细胞 HBV extract Syringa HBeAg HBsAg HepG2.2.15 cells
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  • 1Y. M. Ha-Lee,J. Lee,H. Pyun,Y. Kim,J. Sohn,Y. J. Cho. Sequence variations of hepatitis B virus promoter regions in persistently infected patients[J] 2001,Archives of Virology(2):279~292
  • 2U. Treichel,K.-H. Meyer zum Büschenfelde,H.-P. Dienes,G. Gerken. Receptor-mediated entry of hepatitis B virus particles into liver cells[J] 1997,Archives of Virology(3):493~498

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