肉桂酸苄酯的合成研究

Study on Synthesis of Benzyl Cinnamate

以十六烷基三甲基氯化铵为相转移催化剂催化合成肉桂酸苄酯,考察了催化剂、温度、时间和物料配比等因素对反应的影响。实验结果表明,十六烷基三甲基氯化铵是一种有效的催化剂,在最佳反应条件下,产物收率可达86.0%。最佳反应条件是:n(肉桂酸钠)∶n(氯化苄)为1∶1.2,催化剂的用量为0.8g,反应时间3.0h,反应温度95℃。通过IR、1HNMR和MS对产物结构进行了表征。

The method of catalytic synthesis of benzyl cinnamate with hexadecyl trimethyl ammonium chloride as phase transfer catalyst is studied. The factors influencing the reaction , such as amount of catalyst used, reaction temperature and time ,molar ratio of sodium cinnamate to benzyl chloride are investigated. The result shows that, hexadecyl trimethyl ammonium chloride is an effective catalyst and under the optimal condition, 86.0% yield of benzyl cinnamate can be obtained. The optimal condition is as follows : molar ratio of sodium cinnamate to benzyl chloride 1∶1.2,amount of catalyst 0.8g, reaction time 3.0h,reaction temperature 95℃. The product structure is characterized by IR,~1HNMR and MS.