期刊文献+

克山病病区低硒儿童血小板GSH_(px)和SOD活性以及cAMP含量 被引量:2

PLATELET GSH_(px),SOD ACTIVITIES AND cAMP CONTENTS OF CHILDREN FROM LOW-SELENIUM KESHAN DISEASE AREAS
下载PDF
导出
摘要 本文对比测定了克山病病区与非病区儿童血小板GSH_(px)、SOD活性和cAMP水平,以及全血、红细胞、血浆和头发硒含量。结果表明,病区儿童血和发硒均明显低于非病区;血小板GSH_(px)活性比非病区儿童显著低下,但血小板SOD活性和cAMP水平无显著差异。提示病区低硒儿童血小板GSH_(px)活性的降低可能导致血小板功能和代谢的改变。 In the present study, platelet GSH_(px), SOD activities and cAMP contents, as well as whole blood, erythrocyte, plasma and hair selenium levels were comparatively measured in children from Keshan disease endemic and non-endemic areas. The results showed that blood and hair selenium contents were significantly lower in children of the endemic area than in those of the non-endemic area; children in the endemic area had a signifi cantly lower platelet GSH_(px) activities as compared to those in the non-endemic area, but no remarkable difference of platelet SOD activities and cAMP contents between children in the two areas was observed. The results indicate that the reduced GSH_(px) activity of low-selenium children in the endemic area may result in alterations in platelet functions and arachidonic acid metabolism.
出处 《西安医科大学学报》 CSCD 1992年第4期312-315,共4页 Journal of Xi'an Medical University(Chinese)
关键词 克山病 超氧物歧化酶 血小板 selenium Keshan disease superoxide dismutase glutathione peroxidase platelet cyclic adenosine monophosphate
  • 相关文献

同被引文献8

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部