1[1]Kishimoto Y,Yashima K,Morisawa T.Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane[J].J Gastroenterol,2002,7(3):186.
2[2]Shattuck Brandt RL,Varilek GW,Radhika A,et al.Cyclooxygenase-2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) mice[J].Gastroenterology,2000,118:337.
3[3]Oshima M,Dinchuk JE,Kargman SL,et al.Suppression of intestinal polyposis in Apc (delta 716) knockout mice by inhibition of cyclooxygenase-2 (COX-2) [J].Cell,1996,87:803.
4[4]Singer II,Kawka DW,Schloemann S,et al.Cyclooxygenase-2 is induced in colonic epithelial cells in inflammatory bowel disease[J].Gastroenterology,1998,115:297.
5[5]McCartney SA,Mitchell JA,Fairclough PD,et al.SelectiveCOX-2 inhibitors and human inflammatory bowel disease[J].Aliment Pharmacol Ther,1999,13:1115.
6[6]Shattuck-Brandt RL,Varilek GW,Radhika A,et al.Cyclooxygenase-2 expression is increased in the stroma of colon carcinomas from IL-10 (-/-) mice[J].Gastroenterology,2000,118:337.
8[8]Sonoshita M,Takaku K,Sasaki N,et al.Acceleration of intestinal polyposis through prostaglandin receptor EP-2 in Apc (delta 716) knockout mice[J].Nat Med,2001,7:1048.
9[9]Tsujii M,DuBois RN.Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthetase 2[J].Cell,1995,83:493.
10[10]Sheng H,Shao J,Kirkland SC,et al.Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2[J].J Clin Invest,1997,99:2254.
4Kakiuchi Y, Tsuji S, Tsujii M, et al. Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis [J].Cancer Res,2002,62:1567.
5Tomozawa S, Tsuno NH, Sunami E, et al. Cycooxygenase-2 overexpression correlates with tumour recurrence,especially haematohenous metastasis, of colorectal cancer[J]. Cancer,2000,83(3) : 324.
6Zheng SX, Mouithys-Mickalad A,Deby-Dupont GP,et al.In vitro study of the antioxidant properties of nimesulide and 4-OH nimesulide: effects on HRP- and luminol-dependent chemiluminescence produced by human chondrocytes[J]. Osteoarthritis Cartil,2000,8:419.
7Marx J. Cancer researsh. Antiinflammatories inhibit cancer growth but how[J]. Science, 2001, 291(5504) :581.
8DuBois RN, Shao J, Tsujii M, et al. G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2[J]. Cancer Res,1996,56:733.
9Sheng H, Shao J, Morrow JD, et al. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells[J]. Cancer Res, 1998,58:362.
10Kirkpatrick K, Ogunkolade W, Elkak A, et al. The mRNA expression of cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) in human breast cancer[J]. Curr Med Res Opin,2002,18(4): 237.
