一种靶向肿瘤或炎症组织的新载体——工程巨噬细胞载体
摘要
近年 ,人们利用组织内的巨噬细胞 (macrophages ,M)具有聚集于炎症及肿瘤缺氧区的生物学特性 ,开发了一类新载体———工程M载体。M经携带治疗基因的重组病毒稳定转染 ,并以细胞因子或细菌脂多糖激活后 ,静脉注入体内 ,可靶向炎症组织和肿瘤组织 ,并不断产生和分泌重组病毒 ,有效介导治疗基因的转导 ,为肿瘤。
出处
《国外医学（儿科学分册）》
2004年第1期33-35,共3页
Foreign Medical Sciences（Section of Pediatrics)
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