交感神经系统在应激免疫调节中的作用

THE INVOLVEMENT OF THE SYMPATHETIC NERVOUS SYSTEM IN THE IMMUNOMODULATION INDUCED BY STRESS

目前 ,越来越多的研究资料表明交感神经系统 (SNS)参与了应激的免疫调节作用。有关研究主要集中在SNS与免疫系统间的解剖基础及相互作用、SNS参与应激的免疫调节作用的实验研究以及SNS与下丘脑 -垂体 -肾上腺轴 (HPA)间的相互作用等几个方面。综合阐述这些研究结果 ,并着重分析SNS、应激与免疫系统间的相互作用及其机制。

The evidence of the involvement of the sympathetic nervous system (SNS) in the immunomodulation induced by stress has increased tremendously. The studies were focused on the anatomic basis of the relationship between SNS and immune system,the reciprocal effect of SNS and immune system,and the effect of SNS on the immunomodulation induced by stress. To review the current knowledge of the SNS,immune system and stress, and to elucidate the mechanism of the effect of SNS on the stress-induced immunomodulation.