肝门静脉高压症(PHT)血液动力学研究进展

Progress in the Research on Hemodynamics of Portal Hypertension

肝门静脉高压症 (Portal hypertension,PHT)是世界范围内的一种常见病、多发病 ,严重影响病人的生存质量。血液动力学研究对于揭示 PHT的发病机理 ,探讨其并发症出血的危险性 ,选择恰当的手术方式和手术时机以至检验药物的疗效等方面都有重要意义。我们就从血液动力学角度阐述 PHT的发病机制 ,讨论外科手术治疗方案 ,并介绍近期 PHT血液动力学研究的若干成果 ,最后提出

Portal hypertension (PHT), as a disease with high incidence all over the world, badly affects the patients' health. The research on hemodynamics plays an important role in exploring the pathogenesis of PHT, assessing the risk of hemorrhage induced by the complications, selecting the scheme and time of surgical operations as well as evaluating the curative effects of medication. In this article, the main factors in the pathogeny of PHT are reviewed and the surgical treatments are discussed from the hemodynamic viewpoint. Then some recent results in the hemodynamic research of PHT are summarized. In addition, main ideas are put forward as to establishing a new global biomechanical model of PHT.