期刊文献+

RNA干扰(RNAi)技术及其在功能基因组学研究中的应用 被引量:15

RNA interference technique and using in study of functional genomics
下载PDF
导出
出处 《大连医科大学学报》 CAS 2003年第2期105-107,共3页 Journal of Dalian Medical University
关键词 RNAI技术 功能基因组学 小分子 siRNA 基因缺失 反义寡核苷酸 RNA干扰 RNAinterferencetechnique functionalgenomics smallinterferingRNAs
  • 相关文献

参考文献20

  • 1[1]Guo S, Kempheus KJ. Par- 1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed[J]. Cell,1995,81:611 - 620.
  • 2[2]Fire A. Xu S, Montgomery MK, et al. Potent and specific genetic interference by double - stranded RNA in Caenorhabditis elegans[J]. Nature, 1998,391 (6669): 806-811.
  • 3[3]Lipardi C, Wei Q, Paterson BM. RNAi as random degradative PCR. siRNA primers convert mRNA into dsRNA that are degraded to generate new siRNAs[J].Cell,2001,107:297 - 307.
  • 4[4]Dzitoyeva S, Dimitrijevic N, Manev H. Intra- abdominal injection of double- stranded RNA into anesthetized adult Drosophila triggers RNA interference in the central nervous system[J]. Mol Psychiatry,2001,6(6): 665 - 670.
  • 5[5]Ketting RF, Haverkamp TH, van Luenen HG, et al. Mut -7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNase D[J]. Cell, 1999,99: 133 - 141.
  • 6[6]Knight SW, Bass BL. A role for the RNase Ⅲ enzyme DCR - 1 in RNA interference and germ line development in Caenorhabditis elegans [ J ]. Science, 2001,293 (5538):2269 - 2271.
  • 7[7]Grishok A, Pasquinelli AE, Conte D, et al. Genes and mechanisms related to RNA interference regulate expoession of the small temporal RNAs that control C. elegans developmental timing[ J]. Cell, 2001,106: 23 - 34.
  • 8[8]Schmid Aloisia, Schindelholz B, Zinn K. Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila [ J ]. Trends in Neurosciences, 2002,25(2): 71-74.
  • 9[9]Wojtkowiak A, Sick A, Alejska M, et al. RNAi and viral vectors as useful tools in the functional genomics of plants.Construction of BMV - Based Vectors for RNA Delivery into Plant Cells[J]. Cell Mol Biol Lett,2002,7(2A): 511- 522.
  • 10[10]Wagner EJ, Garcia- Blanco MA. RNAi - mediated PTB depletion leads to enhanced exon definition [ J]. Mol Cell,2002,10(4): 943 - 949.

同被引文献182

引证文献15

二级引证文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部