摘要
本文对64041例围产儿监测资料进行的流行病学研究,共发现先天性畸行儿698例,出生时缺陷总发生率为10.899‰。前五位缺陷依次是中枢神经系统畸形(2.58‰)、唇腭裂(2.19‰),多(并)指(趾)(1.41‰)、肢体畸形(1.17‰)及耳部畸形(1.18‰)。监测结果表明,新生儿畸形的发生与患儿父母是否近亲婚配、家系中有无同种畸形患者、母亲生育年龄、职业、居住地区和妊娠季节等因素有关,支持出生缺陷是多因子疾病的学说。
On survey aud analysis of 64 041 pcrinatal infants in 30 hospitals. It was found 698 cases with congenital malformation, the overall birth defects (BD) prevalence rates were 10.90‰. The 5 leading BD were: central nervous system defects. (2.58‰), cleft lip and/or clefLt palate (2.19‰), synpolydactyly (1.41‰) , deformity of limbs (1.17‰) and ear defects (1.16‰). The results suggest that the incidence rates of BD had a relationship with the following factors: parental-consanguinity, family history of congenital abnormality and maternal age, occupation, address, gcstational season ect. The results supported that the ediology of BD is multifactorial.
出处
《安徽医学》
北大核心
1989年第1期4-7,共4页
Anhui Medical Journal
