老年原发性高血压患者动态脉压与心脏损害的关系

Relationship between ambulatory pulse pressure and heart damage in elderly essential hypertension

目的:探讨老年原发性高血压患者动态脉压与心脏损害的关系。方法:入选老年原发性高血压患者82例,按动态脉压分为40～60mmHg组(n=39)和脉压>60mmHg组(n=43),对超声心动图左室质量指数、左室舒张末内径等指标进行组间对比分析。结果:脉压>60mmHg组左室质量指数(116±19)g/m2、左室舒张末内径(52±5)mm均高于脉压40～60mmHg组(t=2.31,2.12,P均<0.05)。心脏损害的发生率高于脉压40～60mmHg组(51%和28%;t=2.47,P<0.05)。结论:老年原发性高血压患者心脏损害与脉压有关,脉压增大是心血管事件的主要危险因素。

AIM:To explore the relationship between ambulatory pulse pressure and heart d amage in elderly essential hypertension. METHODS:Eighty- two elderly patients with essential hypertension were divide d into two groups according to the levels of ambulatory pulse pressure [pulse pr essure (pp) 40-60 mmHg (Group 1,n=43) and pp >60mmHg (Group 2,n=39)]. Echocar diography was conducted to contrastive analysis according to left ventricular ma ss index(LVMI) and left ventricular end-diastolic diameter (LVEDD). RESULTS:The LVMI(116± 19)g/m2 and LVEDD(52± 5)mm in Group 2 were higher tha n those in group 1(t=2.31,P< 0.05; t=2.12,P< 0.05) . The incidence of heart dama ge in group 1(51% ) was higher than that in Group 2(28% )(t=2.47,P< 0.05). CONCLUSION:Heart damage is related to pulse pressure in elderly essential hyp ertension.And the augmentation of pulse pressure is one of the risk factors of c ardiovascular event.