康复对阿尔茨海默病生活自理能力和认知功能影响的临床研究

Rehabilitation efficacy on ability of daily life and cognition in Alzheimer disease

目的 观察康复治疗阿尔茨海默病患者生活自理能力和认知功能的效果。方法 患者随机分为 2组 ,对照组 30例 ,采取常规治疗和护理 ,康复组 31例 ,予日常生活能力训练、认知功能训练 ,连续 8周 ,观察两组患者MMSE、ADAS认知功能、Blessed -Roth日常生活自理能力治疗前后的评分情况。结果 8周康复治疗后 ,康复组日常生活自理部分Blessed -Roth的评分减低 1.5 8分 ,较对照组和治疗前后有显著性差异 (P <0 .0 5 ) ;认知功能部分MMSE和ADAS评分无显著性差异。结论康复治疗可改善AD日常生活自理能力 ,对认知功能无明显效果。

Objective To investigate the rehabilitation effect on Alzheimer's ability of daily life and cognition. Methods Sixty one patients with AD were randomly divided into two groups. Group A( n =31)underwent rehabilitation treatment and group B( n =30)did not. The efficacy was judged before and after treatment by the mini mental state examination (MMSE), the Alzheimer's disease assessment scale cognition (ADAS-Cog) and Blessed-Roth scale. The data were statistically analyzed. Results After the treatment of rehabilitation for 8 weeks, ability of daily life in Blessed-Roth Scores fell down 1.58 ( P <0.05) while the cognitive portion in ADAS-Cog scores and MMSE scores were not significant difference between groups A and B. Conclusion Rehabilitation was effective in the improvement ability of daily life of AD patients, but no effect on cognition.