急性一氧化碳中毒后周围神经病变12例临床分析

Peripheral Nervous System Lesion Caused by Acute Carbon Monoxide Poisoning: Clinical Analysis of 12 Cases

目的 探讨急性一氧化碳中毒后周围神经病变的临床特点、诊断及治疗。方法 对 12例一氧化碳中毒后周围神经病变患者的临床表现及实验室检查资料进行分析 ,部分病例行EMG检查 ,同时予高压氧联合药物治疗。结果 本组 12例患者均存在各种不同表现的周围神经病变 ,肌电图提示神经元性损害。高压氧联合药物治疗结果治愈 5例 ( 4 1.7% ) ,显效 2例 ( 16.7% ) ,好转 2例 ( 16.7% ) ,无效 3例 ( 2 5 .0 % ) ,总有效率 75 %。结论 急性一氧化碳中毒可致周围神经病变 ,高压氧综合治疗效果较好。

Objective To investigate the clinical features, diagnosis, and treatment of peripheral nervous system lesions caused by carbon monoxide poisoning. Methods The clinical manifestations of 12 cases were analyzed retrospectively. They were all treated as HBO combined with conventional therapy. Some cases had also undergone the examination with EMG. Results All of the patients had got neuropathy. EMG showed neurogenic disorder. The result of treatment was as follows: cure in 5(41.7%), markedly effective in 2(16.7%), improved in 2(16.7%), and unchanged in 3 (25.0%). The general effective rate was 75%. Conclusions Peripheral neuropathy can be observed in carbon monoxide poisoning patients. The efficacy of HBO combined with conventional therapy was apparent.