摘要
Dear Editor,Noroviruses are positive-sense, single-stranded RNA viruses belonging to Caliciviridae and account for more than 50%of all acute gastroenteritis (AGE) outbreaks worldwide and cause an estimated 200,000 deaths per year among children\5 years of age, primarily in developing countries (Hall et al. 2012;Glass et al. 2009). The norovirus genome contains three open reading frames (ORFs).
基金
supported by the Special National Project on Research and Development of Key Biosafety Technologies (2016YFC1201900)
the National Natural Science Foundation of China (31500139)