单发性网状组织细胞瘤1例

A Case of Solitary Reticulohistiocytoma

患者女,8岁,右侧腹壁鲜红色结节2个月。手术切除组织病理示:真皮内可见组织细胞呈肉芽肿样增生,并可见多核巨细胞,其内含均匀细颗粒状物质,呈"毛玻璃"状。免疫组织化学示:CD68阳性,CD1a及S-100均阴性。根据临床与病理特点诊断为网状组织细胞瘤。本病为良性肿瘤,预后良好。

An 8-year-old girl presented with a history of bright red nodule on the right abdominal for 2 months. Histopathologic examination of the excised lesion showed that dermal granuloma hyperplasia was infiltrated with histiocytes and polynuclear giant cells containing uniform finegranular materialin a'frosted-glass' appearance. Immunohistochemical staining was positive for CD68,but negative for CD1 a and S-100. A diagnosis of solitary reticulohistiocytoma was established based on clinical features and histopathologic findings. It turned out to be a benign tumor and had good prognosis.