2Kinoshita N,Sasai N,Misaki Ket al.Apical accumulation of rho in the neural plate is important for neural plate cell shape change and neural tube formation. Molecular Biology of the Cell . 2008
3ER Detrait,TM George,HC Etchevers,JR Gilbert,M Vekemans,MC Speer.Human neural tube defects: developmental biology, epidemiology, and genetics. Neurotoxicology and Teratology . 2005
4Guillonneau M,Jacqz-Aigrain E.Teratogenic effects of vitamin A and its derivates. Archives of Pediatrics . 1997
5Bustelo XR,Sauzeau V,Berenjeno IM.GTP-binding p roteins of the Rho/Rac family:regulation,effectors and functions in vivo.. Bioessays . 2007
6JM Nowak,A Grzanka,A Zuryn,A Stepien.The Rho protein family and its role in the cellular cytoskeleton. Postepy Hig Med Dosw (Online) . 2008
7Li Z,Ren A,Zhang L, et al.Extremely high prevalence of neural tube defects in a 4-county area in Shanxi Province, China. Birth Defects Res A Clin Mol Teratol . 2006
8See AW,Kaiser ME,White JC,et al.A nutritional model of late embr-yonic vitamin A deficiency produces defects in organogenesis at a highpenetrance and reveals newroles for the vitamin in skeletal development. Developmental Biology . 2008
