摘要
考察5个厂家10个批号的盐酸赛庚啶片的溶出度。方法:按照中国药典方法用紫外一可见分光光度法测定含量,以小杯法测定溶出度。结果:T<sub>50</sub>为6.76～22.87min,T<sub>d</sub>为10.63～28.01min。结论:5个厂家10个批号的产品体外溶出度达到《中国药典》2010年版的规定,经统计学处理,不同厂家的盐酸赛庚啶片抽验品的溶出参数差异不显著（P】0.05）。
Abstract Objective:To study the 5 manufacturers of 10 batches of Cyproheptadine Hydrochloride Tablets. Methods:According to Chinese Pharmacopoeia method with UV-visible spectrophotometry content,to the dissolution of a small cup method.Results:T50 is 6.76～22.87min,Td of 10.63～28.01min.Conclusion:10batches of product of 5 manufacturers in vitro dissolution to "Chinese Pharmacopoeia" 2010 edition of the regulations,the statistical treatment of different manufacturers Cyproheptadine Hydrochloride tablets dissolution testing products on different parameters(P >0.05 ).
出处
《湖北三峡职业技术学院学报》
2012年第1期87-88,100,共3页
Journal of Hubei Three Gorges Polytechnic
关键词
盐酸赛庚啶片
含量
溶出度
Cyproheptadine Hydrochloride tablets
content
dissolution
