趋化因子在膀胱癌诊断中作用的研究进展

Progress in the role of chemokines in the diagnosis of bladder cancer

膀胱癌是临床泌尿系统最常见的肿瘤类型,具有较高的致死率和致残率,严重威胁人们的身体健康和生命安全。但是由于膀胱癌在早期诊断、复发监测以及预后评估中缺乏理想的肿瘤标志物,增加了膀胱癌的治疗难度。因此膀胱癌肿瘤标志物的研究是目前医学界研究的热点问题之一。趋化因子是一类具有免疫作用的超蛋白家族,它与肿瘤的生长和转移具有密切关系,对趋化因子的研究对于膀胱癌的诊疗和预后具有积极的意义。基于此,本文重点对近些年关于趋化因子在膀胱癌诊断中的作用研究进展进行综述,以期能够为临床膀胱癌的诊疗提供资料借鉴。

Bladder cancer is the most common type of tumor in the urinary system,with high mortality and disability,and it seriously threatens people's health and life safety.However,the lack of ideal tumor markers in early diagnosis,recurrence monitoring and prognostic evaluation of bladder cancer increases the difficulty of treatment of bladder cancer.Therefore,the research of tumor markers in bladder cancer is one of the hot topics in medical research.Chemokine is a type of superprotein family with immunity,and is closely related to the growth and metastasis of bladder cancer.The study of chemokines is of positive significance for the diagnosis,treatment and prognosis of bladder cancer.Based on this review,the role of chemokines in the diagnosis of bladder cancer in recent years was reviewed in order to provide reference for clinical diagnosis and treatment of bladder cancer.