术后慢性疼痛流行病学及风险因素的进展研究

Progress in postoperative chronic pain epidemiology and risk factors

术后慢性疼痛(CPSP)是外科手术后较为常见的一种并发症,是一种术后远期并发症。通常术后疼痛会随着切口的愈合消失,但也有部分患者会在术后生理恢复期(通常为3个月)过后仍存在疼痛体验。然而尚未在近年来的研究中找到并明确CPSP的发生机制,通常认为和手术过程中神经损伤和术后炎性反应有关。和其他慢性疼痛一样,CPSP会给患者带来身体和心理的双重负担,病程越长越明显,长期的疼痛体验会影响到患者的生活质量和心路历程,严重时可导致患者出现术后心理障碍和社会适应障碍,是一种严重影响患者术后生活质量提高的临床因素。为探讨CPSP的预防和治疗手段,本文对CPSP流行病学和风险因素进行综述性研究。

Postoperative chronic pain(CPSP)is a common complication after surgery and a long-term postoperative complication.Pain usually disappears with the healing of the incision,but some patients still experience pain after the physical recovery period(usually three months).However,the mechanism of CPSP has not been found and clarified in recent years.It is generally considered to be related to nerve injury and postoperative inflammatory reaction.As with other chronic pain,CPSP brings both physical and psychological burden to patients.The longer the course of disease is,the more obvious is the long-term pain experience,which will affect the patient’s quality of life and mental process.It can lead to postoperative psychological disorder and social adaptation disorder,which is a clinical factor that seriously affects the improvement of postoperative quality of life.In order to investigate the prevention and treatment of CPSP,the epidemiology and risk factors of CPSP are reviewed.