天津市儿童医院门急诊“达菲”的使用情况分析

Application of "Tamiflu" in outpatient and emergency department of Tianjin Children’s Hospital

目的分析天津市儿童医院'达菲'(磷酸奥司他韦胶囊,规格为75 mg)在门急诊的使用情况,探讨其在患儿中的应用模式和规律。方法抽取2019年上半年天津市儿童医院门急诊使用过'达菲'进行药物治疗的病历600例,对其处方进行回顾分析,对'达菲'的使用年龄、给药方式、用药剂量、使用科别、联合用药的种数及联用类别、治疗疾病种类和治疗进展等方面进行分类统计。结果使用'达菲'的患儿以1~6岁儿童居多,其科室以内科为主。'达菲'的给药方式为口服,其处方剂量符合指南推荐用药,用药方案以联合一种或两种药物为主且以联用退烧药、抗生素和中成药居多。结论从药物流行病学角度考察了'达菲'在临床上的应用规律和模式,对确定其在流感样病例患儿中应用的安全性和有效性具有积极意义。

Objective To explore the regularity and pattern of utilization of'Tamiflu'in children by analyzing the application of the drug(oseltamivir phosphate capsule,75 mg)in outpatient and emergency department of Tianjin Children’s Hospital.Methods A total of 600 patients who treated with'Tamiflu'in outpatient and emergency department of Tianjin Children Hospital in the first half of 2019 were selected and their prescriptions were analyzed retrospectively.And the prescription analysis was focused on the age,administration method,dosage,clinical departments,number and category of combined drugs,types of diseases and the treatment progress of the use of'Tamiflu'retrospectively.Results Most of the children who used'Tamiflu'were 1-6 years old,and their departments were mainly internal medicine.'Tamiflu'was adminis tered orally,and its prescription dose was in line with the guidelines.'Tamiflu'was mainly combined with one or two drugs,and the combination of antipyretics,antibiotics and Chinese patent drugs were the majority in the study.Conclusion The application rule and mode of'Tamiflu'in clinic were investigated from the perspective of pharmacoepidemiology,which was of positive significance to determine the safety and effectiveness of'Tamiflu'in children with influenza-like cases.