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α-萘异硫氰酸酯实验性黄疸模型及其在中药研究中的应用 被引量:5

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摘要 作者根据α-萘异硫氰酸酯(简称ANIT)使小白鼠和大白鼠产生显著的高胆红素血症和胆汁郁积的报导,用ANIT造成了实验性黄胆模型。文中详细地介绍了其实验方法和作用机制。作者认为,这一模型重复性好、稳定、方法简单、易于掌握。在肝病的药物筛选和研究中,将有助于全面地认识和评价中药的药理作用,为中药的理论研究和临床应用提供实验依据。
出处 《中成药》 CAS 1981年第4期39-41,共3页 Chinese Traditional Patent Medicine
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同被引文献21

  • 1王超云,傅风华,田京伟,张太平,孙芳,刘珂.黄芩苷对化学性肝损伤的保护作用[J].中草药,2005,36(5):730-732. 被引量:35
  • 2张红军,于彬,梅峰,周德山.豚鼠Oddi括约肌内Cajal样细胞及NOS表达阳性神经元的分布[J].消化外科,2006,5(3):201-205. 被引量:9
  • 3Huizinga ,ID. Chen JH. Mikkelsen HB, el al. Interstitial cells of Cajalfrom structure to function [J].Froni Neu-rosci,2013.7:,13.
  • 4Pasternak A, Gajda M,Gil K,et al. Evidence of interstial Cajalqike cells in hurnan gallbladder[J]. Folia Histochem Cytobiol, 2012.50(4) : 581-585.
  • 5I.ee BH, Huang YY,Duh PD.et al. Hepatoproteetion of emodin and Polygonum mulliflorum against (4)-in duced liver injury[J]. Pharm Biol,2012,50(3) :.'351-359.
  • 6Rutherford AE, Pratt DS. Cholestasis and cholestatic syn- dromes[J]. Curr Opin Gastroemerol, 2006,22 (3) : 209-214.
  • 7Sanders KM,Koh SD.Ward SM. Interstiid cells of cajd as pacemakers in tile gastrointestinal tact[J]. Annu Rev Physiol, 2006,68 : 307-343.
  • 8Huizinga JD,Faussone Pellegrini MS. About the presence of interstitial ceils of Cajal outside the musculature of the gastrointestinal tract[J]. J Cell Mol Med, 2005,9 (2) : 468- 473.
  • 9Heinrich MC, Rubin BP, Longley BJ, et al. Biology and genetic aspects of gastrointestinal stromal tumors:KIT activation and cytogenetic alterations [J]. Hum Pathol, 2002,33(5) :484-495.
  • 10Jung HA, Chung HY, Yokozawa T, et al. Alaternin and emodin with hydroxyl radical inhibitory and/or scaven- ging activities and hepatoprotective activity on tacrine-in- duced cytotoxicity in HepG2 cells[J]. Arch Pharm Res, 2004,27(9) :947-953.

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