倒心盾翅藤中的1个新鼠李糖苷

A new rhamnoside from Aspidopterys obcordate

目的研究傣药倒心盾翅藤Aspidopterys obcordate的化学成分。方法采用硅胶柱色谱、Sephadex LH-20柱色谱、ODS等色谱分离技术,对倒心盾翅藤茎醇提物的醋酸乙酯相和正丁醇相进行分离纯化,经现代波谱技术及物理常数测定等方法对所分离的化学成分进行结构鉴定。结果从倒心盾翅藤95%乙醇提取物中分离得到8个化合物,分别鉴定为3,4-二羟基苯甲酸-3-O-α-L-鼠李糖苷(1)、3,4-二羟基苯酚乙酸酯(2)、3,4-二羟基苯甲酸(3)、儿茶素(4)、β-谷甾醇(5)、胡萝卜苷(6)、cinnacasolide C(7)、尿囊素(8)。结论所有化合物均为首次从倒心盾翅藤中分离。其中,化合物1为新化合物,命名为倒心盾翅藤苷。

Objective To study the chemical constituents of Aspidopterys obcordate.Methods The chemical constituents from 95%EtOH extract of the stem of A.obcordate were isolated by repeated chromatograph with silica gel,Sephadex LH-20,and ODS.The structures were elucidated by spectroscopic analysis.Results Eight compounds were isolated and identified as 3,4-dihydroxybenzoic acid-3-O-α-L-rhamnoside(1),3,4-dihydroxyphenyl acetate(2),3,4-dihydroxybenzoic acid(3),catechin(4),β-sitosterol(5),daucosterol(6),cinnacasolide C(7),and alantan(8).Conclusion Compound 1 is a new compound,named as apobcoroside.All compounds are isolated from the plant of A.obcordate for the first time.