油茶根中1个新的三萜皂苷

A new triterpene saponin from roots of Camellia oleifera

目的 研究油茶Camellia oleifera根的化学成分。方法 利用硅胶、ODS、Sephadex LH-20葡聚糖凝胶柱色谱、高效制备液相色谱等色谱方法进行分离纯化,根据理化常数测定及谱学数据分析鉴定化合物结构。结果 从油茶根中分离得到3个化合物,分别鉴定为3-O-β-D-半乳糖基-(1→2)-[β-D-木糖基-(1→2)-α-L-阿拉伯糖基-(1→3)]-β-D-葡萄糖醛酸基-3β,15α,16α,21β,22α,28-六羟基-21-O-乙酰氧基-22-O-当归酰氧基齐墩果醇-12-烯(1)、大头茶苷J(2)、山茶皂苷B1(3)。结论 化合物1为新化合物,命名为山茶皂苷Ac,化合物2和3为首次从油茶中分离得到。

Objective To study the chemical constituents from the roots of Camellia oleifera.Methods The chemical constituents were isolated and purified by column chromatography on silica gel,ODS,Sephadex LH-20,and PHPLC.Their structures were elucidated on the basis of physicochemical properties and spectroscopic analysis.Results Three compounds were isolated from the roots of C.oleifera and elucidated as 3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→2)-α-L-arabinopyranosyl-(1→3)]-β-D-glucuronopyranosyl-3β,15α,16α,21β,22α,28-hexahydroxy-21-O-acetyl-22-O-angeloyloxyolean-12-ene(1),gordonoside J(2),and camelliasaponin B1(3).Conclusion Compound 1 is a new compound named camelliasaponin Ac,and compounds 2 and 3 are isolated from the roots of this plant for the first time.