UF-100尿液分析仪筛检尿路感染临床意义的探讨

Investigation on the value of screening urinary tract infection with fully automated urine cell analyzer UF-100

目的 探讨UF 10 0尿液分析仪筛检尿路感染的临床意义。方法 对UF 10 0作重复性试验 ,用UF 10 0检测 32 5份尿中细菌和白细胞 ,同时作定量细菌培养并将结果作比较。用Yerushalmy模式评价 2种方法的一致性及UF 10 0筛检的灵敏度、特异性等。结果 重复试验中 ,UF 10 0细菌计数CV值低于白细胞计数CV ,与定量细菌培养结果比较 ,细菌计数的筛检灵敏度为 80 .0 % ,特异性为 5 0 .4 % ,阳性预计值为 2 8.7% ,阴性预计值为 91.0 % ,假阳性率为 39.7% ,假阴性率为 4 .0 % ,准确率为 5 6 .3%。结论 UF 10 0具有良好的分析尿液的性能 ,在临床尿路感染筛检时可用细菌一项指标 ,90 %结果阴性的标本可在短时间内筛去 ,大大减少实验人员繁复劳动 ,降低检验成本 ,但应注意假阴性 ,更不可替代尿定量细菌培养。

Objective To investigate the clinical significance of screening urinary tract infection with UF 100. Methods 325 urine specimens were examined for bacteria and WBC with UF 100 and by quantitative culture of bacteria. The sensitivity and specificity of UF 100 and coherence of two methods were evaluated by Yerushalmy mode. Results The screen test of UF 100 showed a sensitivity of 80.0%, specificity of 50.4%, positive predictive value of 28.7%, negative predictive value of 91.0%, false positive rate of 39.7%, false negative rate of 4.0%, accuracy of 56.3%. Conclusions The urinanalysis capability of UF 100 was excellent. When the urine samples were screened, the “BACT” could be adopted. About 90% negative cases could be eliminated quickly and cheaply. But it could not replace the quantitative bacteria culture. If the false negative rate could be reduced, it would be a good screen test for urinary tract infection.