兰州市2010—2014年围产儿出生缺陷现况分析

Analysis of the Perinatal Birth Defects in Lanzhou from 2010 to 2014

目的分析兰州市2010—2014年出生缺陷的发生率及发生顺位,了解出生缺陷发生的影响因素。方法收集兰州市2009年10月1日—2014年9月30日所有孕满28周至产后7天的围产儿(出生或引产)资料,分析出生缺陷发生现况。结果兰州市2010—2014年出生缺陷的发生率分别为82.61/万、106.74/万、129.98/万、111.91/万和138.25/万;兰州市围产儿中唇腭裂、先天性心脏病、多发缺陷的发生率及顺位,2010—2014年均处在前3位。结论兰州市2010—2014年出生缺陷的发生率总体呈上升趋势,其中先天性心脏病的发生率总体呈上升趋势,神经管畸形的发生率总体呈下降趋势。应重点加强对唇腭裂、先天性心脏病的预防。

OBJECTIVE To analysis the incidence of birth defects and the sequence of the occurrences,understand the factors of birth defects in Lanzhou from 2010 to 2014. METHODS Collect perinatal data that all pregnant from at least 28 weeks of gestation to 7days after delivery,included the birth or induced labor data,analysis status of birth defects in Lanzhou from October 1, 2009 to September 30,2014. RESULTS The incidence of birth defectseach was 82.61/10 000 births,106.74/10 000 births,129.98/10 000 births,111.91/10 000 births,138.25/10000 births from 2010 to 2014. The incidence and the sequence in the first three places were cleft lip and palate,congenital heart disease,multiple defects from 2010 to 2014. CONCLUSION The incidence of birth defects and congenital heart disease gradually increased,neural tube defects gradually decreased from 2010 to 2014 in Lanzhou, the measures of strengthen the cleft lip and palate and congenital heart disease prevention should be taken.