摘要
随着生命科学的发展,对实验动物质量的要求也越来越高,实验动物标准的不断完善就变得尤为重要,小鼠诺如病毒在实验小鼠中有很高的感染率,小鼠感染后不仅对动物本身造成危害,对实验结果也会产生较大影响。我国的实验动物国家标准目前还未将小鼠诺如病毒纳入常规检查项目,我们参考国内外小鼠诺如病毒的最新研究成果及国外相关标准,编制了小鼠诺如病毒的团体标准。本文介绍了小鼠诺如病毒检测方法团体标准编制的背景、法律法规依据,对标准内容的设置进行了解释。本标准的编制完善了实验动物相关标准,为推动实验动物质量的提高,适应实验动物国际化发展的需求提供了技术支持。
With the increasing need for high-quality lab animals, the continuous improvement of lab animal standards has become particularly important. Murine norovirus(MNV) has a high infection rate in lab mice. MNV infection not only harms the animals themselves, but also has a great impact on the experimental results. The national standards for laboratory animals in China do not yet include murine norovirus in the list of routine examination items. We have compiled group standards for murine norovirus by referring to the latest research results on murine norovirus at home and abroad, along with relevant foreign standards. This paper introduces the background, and legal and regulatory basis for the preparation of murine norovirus group standards and explains the sets for the standard content. The establishment of such standards should improve the quality of lab animals. They can provide technical support for promoting improved quality of lab animals and adapting to the needs of the international development of lab animals.
作者
李晓波
付瑞
王吉
王淑菁
王莎莎
李威
秦骁
黄宗文
贺争鸣
岳秉飞
LI Xiaobo;FU Rui;WANG Ji;WANG Shujing;WANG Shasha;LI Wei;QIN Xiao;HUANG Zongwen;HE Zhengming;YUE Bingfei(Institute of Laboratory Animal Resources,National Institutes for Food and Drug Control,Beijing 102629,China)
出处
《中国比较医学杂志》
CAS
北大核心
2019年第3期79-83,共5页
Chinese Journal of Comparative Medicine
关键词
实验动物
团体标准
小鼠诺如病毒
laboratory animal
group standards
murine norovirus