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视网膜静脉阻塞继发黄斑水肿的临床治疗观察

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摘要 目的研究玻璃体腔注射Lucentis治疗视网膜静脉阻塞继发黄斑水肿(macular edema,ME)的疗效。方法回顾性分析2014-10—2015-10在秦皇岛市第一人民医院眼科门诊经眼底荧光血管造影(fundus fluorescein angiography,FFA)和光学相干断层扫描(optical coherence tomography,OCT)确诊视网膜静脉阻塞继发黄斑水肿的患者,共有68例68只眼,分为两组。A组为接受玻璃体腔注射Lucentis 0.5 mg组,37人37只眼。B组为接受球后注射曲安奈德(Triamcinolone acetonide,TA)20 mg治疗组,31人31只眼。监测患者在治疗前,治疗后1周,治疗后1个月,治疗后3个月,治疗后6个月的不同时期黄斑水肿的黄斑视网膜中心厚度(central macular thickness,CMT)和最佳矫正视力(best corrected visual acuity,BCVA),记录相应时期的眼压变化情况。所有数据采用SPSS 13.0软件处理。结果 A组治疗前CMT由(608.13±0.81)μm降至(278.15±48.01)μm,差异有统计学意义。BCVA由(0.12±0.08)提高到(0.40±0.21),差异有统计学意义。B组治疗前CMT由(618.00±0.09)μm降至(373.18±82.44)μm,差异有统计学意义。BCVA由(0.15±0.05)提高到(0.26±0.14),差异无统计学意义。结论玻璃体腔注射Lucentis对于治疗视网膜静脉阻塞继发继发ME具有显著疗效,能显著消退黄斑水肿及提高患者视力。
作者 王伟 王林洪
出处 《中国疗养医学》 2016年第7期756-757,共2页 Chinese Journal of Convalescent Medicine
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