经颅多普勒超声与计算机血管成像联合诊断对颅内动脉狭窄疾病的诊断价值

Diagnosis of Intracranial Artery Stenosis Disease with Transcranial Doppler Ultrasound and Angiography Combined with Computer

目的:探讨单独及联合应用计算机血管成像(computed tomographic angiography,CTA)及经颅多普勒超声(transcranial doppler,TCD)对颅内动脉狭窄疾病的临床诊断价值。方法:选择2015年06至2016年06月期间在齐齐哈尔医学院附属第二医院确诊为急性缺血性脑卒中患者47例作为研究对象,所以患者均经TCD及CTA检查,后行数字减影血管造影(digital subtraction angiography,DSA)检查。结果:以DSA检查结果作为金标准,评价TCD、CTA的检查结果,47例患者中经DSA检查出共有67支颅内动脉狭窄,TCD检出53支颅内动脉狭窄,CTA检出52支颅内动脉狭窄,TCD与CTA联合诊断检出64支颅内动脉狭窄。CTA与TCD联合诊断明显高于单独一种检查手段(χ~2=8.152,P=0.004;χ~2=9.241,P=0.002)。结论:TCD与CTA联合诊断颅内动脉狭窄疾病可避免漏诊,能够为临床提供良好的依据,为临床进一步治疗提供客观的依据。

Objective: The single and combined application of computer angiography(computed tomographic angiography, CTA) and transcranial Doppler ultrasound(transcranial Doppler, TCD) in the diagnosis of intracranial artery stenosis disease is explored.Methods: From June 2015 to June 2016, choosing the 47 cases of patients with acute ischemic stroke as the research object in the Second Affiliated Hospital of Qiqihar Medical School, thus, patients underwent TCD and CTA examination then underwent digital subtraction angiography(digital subtraction angiography, DSA). Results: According to the results of DSA examination as the gold standard, evaluating TCD and CTA, in 47 patients with DSA, checking out 67 intracranial artery stenosis totally, TCD detecting 53 branches intracranial artery stenosis, CTA detecting 52 branches intracranial artery stenosis, the number of TCD combined with CTA in diagnosis of intracranial arterial stenosis is 64. The combined diagnosis of CTA and TCD is significantly higher than that of a single test method(χ~2=8.152, P=0.004, χ~2=9.241, P=0.002). Conclusion: TCD combined with CTA in the diagnosis of intracranial artery stenosis will avoid missed diagnosis, can provide a good basis for clinical treatment, and provide an objective basis for clinical treatment.