胰岛素瘤定位及手术方式选择

Localized diagnosis and surgical management of insulinoma

胰岛素瘤属功能性胰腺神经内分泌肿瘤,由于肿瘤过度分泌胰岛素导致反复发作的低血糖症,症状显著,危害性大,通常临床上持积极干预观点。定位诊断和外科治疗是胰岛素瘤诊治过程中面临的两个关键问题。定位诊断方面,传统影像学检查手段有了新进步,分子成像等新技术方法不断出现。外科治疗方面,随着微创技术的不断推广,手术方案的选择、术式利弊的权衡及术中操作的要点也成为业内学者讨论的热点问题。

Insulinoma is a type of functional pancreatic neuroendocrine neoplasms(p NENs).As symptoms of hypoglycemia due to hyperinsulinemia are varied and nonspecific,diagnosis of insulinoma tends to be quite difficult.Both of localization diagnosis and surgical management are key points to deal with insulinoma.As for localization,while traditional imaging methods like CT and MRI improve quite fast,new molecular imaging technologies also develop rapidly.In terms of surgical treatment,main concerns of physicians often focus on the evaluation of operative procedures and experience of operating points.