期刊文献+

肠瘘患者术后腹腔感染对降钙素原与 C反应蛋白和白细胞计数值影响研究 被引量:7

Changes of procalcitonin, C-reactive protein and white blood cell count in patients with abdominal infection after intestinal fistula surgery
原文传递
导出
摘要 目的探讨肠瘘患者腹腔感染术后的降钙素原(PCT),C反应蛋白(CRP),白细胞计数(WBC)变化情况及预防对策。方法选取2010年1月至2017年12月之间在舟山市妇幼保健院进行确定性手术的肠瘘患者120例,按照患者在确定性手术后是否发生腹腔感染分为对照组与病例组,其中对照组77例患者未发生腹腔感染,病例组43例患者发生腹腔感染,对两组患者的资料进行分析,探讨肠瘘患者确定性手术后腹腔感染的PCT,CRP,WBC变化情况及预防对策。结果从手术前到手术后3 d,两组患者的血清PCT,CRP和WBC均增高,病例组患者增高的幅度大于对照组患者,差异有统计学意义(t=-9.153,-4.318,-5.144,P<0.05),手术后3 d血清的PCT,CRP和WBC浓度增高是肠瘘患者手术后是否发生腹腔感染的独立危险因素(OR=1.146,1.159,1.167,P<0.05),利用手术后3 d血清的PCT,CRP和WBC浓度对于接受手术的肠瘘患者进行诊断,最佳截断值分别为1.74(μg/L),128.79(mg/L)和11.59(×10~9/L),约登指数分别为54.18%,41.14%和45.70%。结论血清PCT,CRP和WBC浓度对于肠瘘患者确定性手术后是否发生腹腔感染具有一定的预测价值,值得进行深入研究,应采用各类措施预防肠瘘患者术后发生腹腔感染。 Objective To observe the changes of procalcitonin(PCT),C-reactive protein(CRP),white blood cell count(WBC)in patients with post intestinal fistula surgery abdominal infection.Methods A retrospective study was conducted among 120 patients with intestinal fistula surgery in Zhoushan Maternal and Child Healthcare Hospital from January 2010 to December 2017,patients were divided into control group(n=77,without postoperative abdominal infection)and the study group(n=43,with postoperative abdominal infection).Clinical data were analyzed to understand the changes of PCT,CRP,WBC after the infection.Results 3 days after the surgery,the increases of serum levels of PCT and CRP as well as WBC in study group were greater than that in the control group,the differences were statistically significant(t=-9.153,-4.318,-5.444,P<0.05).The increases of serum levels of PCT and CRP and WBC 3 days after surgery were independent risk factors for abdominal infection in patients with intestinal fistula surgery(OR=1.146,1.159,1.167,P<0.05).when using the serum PCT,CRP and WBC at 3 d post surgery for the diagnosis of abdominal infection after the surgery,the optimal cutoff values were 1.74(μg/L),128.79(mg/L),11.59(×10~9/L)and Yoden indices were 54.18%,41.14%and 45.70%.Conclusions Serum levels of PCT and CRP and WBC may be used for the prediction of abdominal infection after intestinal fistula surgery.
作者 夏龙飞 刘玉君 张军民 吴其肯 韩俊毅 XIA Long-fei;LIU Yu-jun;ZHANG Ai-min;WU Qi-ken;HAN Jun-yi(Department of General Surgery,Zhoushan Maternal and Child Health Care Hospital,Zhoushang,Zhejiang 316000,China;不详)
出处 《中国预防医学杂志》 CAS CSCD 2019年第5期446-450,共5页 Chinese Preventive Medicine
关键词 肠瘘 腹腔感染 降钙素原 C反应蛋白 白细胞计数 消化道 血清学指标 Intestinal fistula Abdominal infection Procalcitonin C-reactive protein White blood cell count Digestive tract Serological index
  • 相关文献

参考文献16

二级参考文献128

共引文献143

同被引文献78

引证文献7

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部