腰高比对2型糖尿病高危人群筛查的价值研究

Value of waist-to-height ratio in type 2 diabetes mellitus related high-risk population

目的探讨腰高比对2型糖尿病(T2DM)高危人群筛查的价值。方法选择首钢4个社区的无糖尿病病史的T2DM普查人群,根据口服葡萄糖耐量试验(OGTT)结果,分层随机抽取6072例患者,男、女各3036例,其中,糖耐量正常组3080例,糖调节受损组2992例(包括空腹血糖受损及糖耐量减低)。采用Logistic回归分析和受试者工作特征(ROC)曲线对比分析肥胖评价指标体重指数(BMI)、腰臀比(WHR)和腰高比(WHtR)对T2DM高危人群筛查的价值。结果 Logistic回归分析显示WHR、WHtR、BMI与T2DM的高危人群呈显著正相关(P<0.05)。WHtR作为预测变量时,其对应的ROC曲线下面积(AUC)较大,提示筛查效果较好。结论 WHtR筛查T2DM高危人群的效果优于BMI和WHR。

Objective To investigate the value of waist-to-height ratio(WHtR)in type 2 diabetes mellitus(T2DM)related high-risk population.Methods T2DM census populations with no diabetes history in 4 communities in Shougang were selected,and 6072 patients were randomly selected according to the results of oral glucose tolerance test(OGTT),3036 male and female each.Among them,3,080 cases in normal glucose tolerance,2992 cases in sugar-regulated group(including impaired fasting glucose and glucose tolerance).Logistic regression analysis and receiver operating characteristic(ROC)curves were used to compare the value of body mass index(BMI),waist-to-hip ratio(WHR)and waist-height ratio(WHtR)in obesity evaluation indicators for high-risk population screening in T2DM.Results Logistic regression analysis showed that BMI,WHR,WHtR was positively correlated with T2DM related high-risk population(P<0.05).When WHtR was used as the predictor variable,the larger area under the corresponding ROC curve(AUC)indicated that the screening effect was better.Conclusion WHtR is superior to BMI and WHR in prediction of T2DM related high-risk populations.