C-反应蛋白、降钙素原协同血清淀粉样蛋白A检测在小儿细菌感染性疾病中的诊断价值

Diagnostic value of C-reactive protein and procalcitonin combined with serum amyloid A in pediatric bacterial infections

目的探究CRP、PCT及SAA检测在小儿细菌感染性疾病中的诊断价值。方法选取78例细菌感染性疾病患儿作为细菌组,78例病毒感染性疾病患儿作为病毒组,78例健康儿作为对照组,对3组进行PCT、CRP、SAA检测,对比3组PCT、CRP、SAA水平及对小儿细菌感染性疾病检测的性能。结果细菌组和病毒组的CRP、SAA均高于对照组,且细菌组CRP、SAA高于病毒组,组间比较差异均有统计学意义(均P<0.05)。细菌组的PCT高于病毒组及对照组,差异有统计学意义(P<0.05),且病毒组和对照组PCT比较差异无统计学意义(P>0.05)。PCT+CRP+SAA诊断效果最好。结论联合检测PCT、CRP、SAA有利于鉴别小儿细菌感染性疾病,其灵敏度、特异度高,有助于临床诊断,降低误诊率。

Objective To explore the diagnostic value of C-reactive protein(CRP),procalcitonin(PCT)and serum amyloid A(SAA)in pediatric bacterial infections.Methods 78 children with bacterial infections were selected as bacterial group,78 children with viral infections as virus group,78 healthy children as control group.PCT,CRP and SAA were tested and the performance in the detection of bacterial infections were compared in three groups.Results CRP and SAA in the bacterial group and the virus group were higher than those in the control group,and the CRP and SAA in the bacterial group were higher than those in the virus group.The difference between the two groups was statistically significant(P<0.05).The PCT of the bacterial group was higher than that of the virus group and the control group,the difference was statistically significant(P<0.05),and there was no significant difference between the virus group and the control group(P>0.05).PCT and CRP combined with SAA had the best diagnostic results.Conclusion Combined detection of PCT,CRP,and SAA is beneficial to identify pediatric bacterial infections,and its sensitivity and specificity are high,which is helpful to improve the clinical diagnosis and reduce the misdiagnosis rate.