苗药黑骨藤研究进展

Research Progress of Periploca forrestii Schltr.

黑骨藤是苗族常用传统药物,"苗药三珍宝"之一,主要含有强心苷、黄酮、神经酰胺、萜类、苯丙素和挥发油等多种成分,具显著强心、抗炎、镇痛、抗氧化、抗菌等药理作用,临床上主要用于风湿性关节炎、跌打损伤、胃痛、消化不良、闭经、痢疾等疾病治疗。查阅近年来国内外相关文献报道,对黑骨藤化学成分、药理作用、临床应用、质量控制及谱效关系等进行全面综述,为进一步开发利用提供参考。

Periploca forrestii,a traditional medicine commonly used by Miao people,is one of the ' three treasures of Miao medicine',which mainly contains various components such as cardiac glycosides,flavonoids,ceramides,terpenoids,phenylpropanoid and volatile oils. It has significant pharmacological effects including cardiotonic,anti-inflammatory,antioxidant,pain-suppressing,and antibacterial activities,and is used to treat rheumatoid arthritis,bruises,stomach pain,dyspepsia,amenorrhea,and dysentery. Relevant domestic and abroad literatures were summarized,and a comprehensive review of the chemical constituents,pharmacological effects,clinical application,quality control and spectrum-effect relationship of Periploca forrestii was conducted,to provide evidences for further investigation of Periploca forrestii Schltr.