疼痛护理管理对晚期原发性肝癌患者的应用效果

Application of pain management nursing care in patients with primary advanced liver cancer

目的探讨疼痛护理管理对原发性晚期肝癌患者的应用效果。方法选取2016年1月至2017年12月间陕西省西安市中心医院收治的68例晚期肝癌疼痛患者,根据护理方法不同分组。其中,采用疼痛护理管理的36例患者纳入观察组,采用常规护理的32例患者纳入对照组。观察两组患者的焦虑评分、疼痛评分及护理前后外周血中白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)和C-反应蛋白(CRP)水平,同时比较两组患者护理后生活质量评分。结果护理前,两组患者疼痛评分和汉密尔顿焦虑评分比较,差异无统计学意义(P>0. 05)。护理后,两组患者的疼痛评分和汉密尔顿焦虑评分均下降,且观察组上述评分下降幅度大于对照组,差异均有统计学意义(均P <0. 05)。护理前,两组患者的IL-1β、IL-6、TNF-α和CRP比较,差异无统计学意义(P> 0. 05)。护理后,两组患者IL-1β、IL-6、TNF-α和CRP均改善,且观察组上述指标均低于对照组,差异均有统计学意义(均P <0. 05)。护理后,观察组躯体功能、心理功能、社会功能及客观环境均明显高于对照组,差异均有统计学意义(均P <0. 05)。结论采用疼痛护理管理干预原发性晚期肝癌患者,可为患者树立战胜疾病的信心,优化心理现状,缓解疼痛,改善生活质量。

Objective To investigate the application of pain management nursing care in patients with primary advanced liver cancer. Methods In this study,68 patients with advanced liver cancer pain admitted to Xi’an Central Hospital from January 2016 to December 2017 were selected and randomly divided into an observation group( 36 patients) and a control group( 32 patients). The observation group received the pain management nursing and the control group the routine nursing. Then various indicators were compared between the two groups,including anxiety and pain scores,levels of interleukin-1β( IL-1β),interleukin-6( IL-6),tumor necrosis factor-α( TNF-α) and C-reactive protein( CRP) in the peripheral blood,along with the quality of life scores. Results The pain scores and Hamilton anxiety scores had no difference between the two groups before treatment( P > 0. 05),while they were decreased after treatment,and were lower in the observation group than in the control group( all P < 0. 05). There was no difference in the levels of IL-1β,IL-6,TNF-α and CRP in the peripheral blood between the two groups before treatment( P > 0. 05),while they were ameliorated after treatment,and were better in the observation group than in the control group( all P < 0. 05). The physical function,psychological function,social function and objective environment were significantly higher in the observation group than in the control group( all P < 0. 05).Conclusion The pain management nursing can ameliorate the psychological status and improve depression symptoms,as well as alleviate the pain in patients with advanced liver cancer pain.