围手术期护理对超声引导下颅内肿瘤切除术患者白细胞介素-6和C反应蛋白的影响

Effect of perioperative nursing on interleukin-6 and C-reactive protein in patients undergoing ultrasound-guided intracranial tumor resection

目的探讨围手术期护理对超声引导下颅内肿瘤切除术患者白细胞介素-6和C反应蛋白的影响。方法选取2015年3月至2018年6月间陕西省延安市人民医院收治的90例颅内肿瘤患者,所有患者均已接受超声引导下颅内肿瘤切除术治疗。采用随机数表法分为观察组和对照组,每组45例。观察组患者采用围术期护理,对照组患者采用常规护理。比较两组患者手术前后白细胞介素-6和C反应蛋白的变化。结果与对照组患者比较,观察组患者手术时间短,术中出血量少,住院时间短,差异均有统计学意义(均P <0. 05)。术前,两组患者的白细胞介素-6比较,差异无统计学意义(P>0. 05)。术后,两组患者白细胞介素-6均高于术前,且观察组患者的白细胞介素-6均低于对照组患者,差异均有统计学意义(P <0. 05)。术前,两组患者的C反应蛋白水平比较,差异无统计学意义(P>0. 05)。术后,两组患者C反应蛋白均高于术前,且观察组患者的C反应蛋白均低于对照组患者,差异均有统计学意义(P <0. 05)。结论围术期护理干预能够有效改善超声引导下颅内肿瘤切除术患者白细胞介素-6和C反应蛋白水平,从而有效改善患者的临床疗效,临床意义显著。

Objective To investigate the effect of perioperative nursing on interleukin-6 and C-reactive protein in patients undergoing intracranial tumor resection under ultrasound guidance.Methods Ninety patients with intracranial tumors admitted to Yan'an People's Hospital from March 2015 and June 2018 were enrolled.All the patients underwent ultrasound-guided intracranial tumor resection and were randomly divided into an observation group and a control group.The observation group received perioperative care and the control group received routine care.The changes in interleukin-6 and C-reactive protein were compared before and after surgery.Results The operation time,intraoperative blood loss,and hospitalization time were significantly less in the observation group than in the control group(all P<0.05).Before the surgery,there were no significant differences in interleukin-6 levels between the two groups(P>0.05).After the surgery,interleukin-6 was higher in both groups when compared with before the surgery(all P<0.05).Interleukin-6 was lower in the observation group than in the control group(P<0.05).Similarly,there were no significant differences in C-reactive protein between the two groups(P>0.05).After the surgery,C-reactive protein was higher in both groups when compared with before the surgery(all P<0.05).Moreover,C-reactive protein levels were lower in the observation group than in the control group(P<0.05).Conclusion Perioperative nursing intervention can effectively improve the levels of interleukin-6 and C-reactive protein,thus effectively improving the clinical efficacy,with significant clinical significance.