山西地区2012年至2013年我院就诊人群血清维生素D水平状况调查

The investigation of vitamin D status in patients in Shanxi from 2012 to 2013

目的探讨目前山西地区不同季节人群的维生素D状况。方法通过对2012年6月至2013年7月山西医科大学第二医院就诊的1313例患者血清25羟维生素D[25(OH)D]和甲状旁腺激素(PTH)水平,应用电化学发光免疫法测定血清25-羟维生素D[25(OH)D]、甲状旁腺激素(PTH),按不同季节、性别进行分析。结果 1所有检测人员的血清25(OH)D平均水平:男性(11.38±6.29)ng/m L,女性(9.04±5.71)ng/m L。按照IOF维生素D水平判定标准:严重缺乏者占62.2%;维生素D缺乏者占28.46%;维生素D不足者占6.1%;维生素D充足者占3.25%。2血清25(OH)D水平与季节有显著相关性(r=0.228,P<0.05);3血清25(OH)D与PTH呈负相关(r=-0.272,P<0.05)。结论受各种因素影响,目前山西地区成年人群中存在严重的维生素D不足和缺乏状况,应受到广泛的关注并改善现状,降低维生素D相关疾病的发病率。

Objective To analyze the current vitamin D status in the population of Shanxi in different seasons. Methods Serum 25( OH) D and PTH levels of 1313 patients in the Second Hospital of Shanxi Medical University were analyzed from June2012 to July 2013. They were detected using electrochemical luminescence immune method. The date were analyzed according to different season and gender. Results 1) The average level of serum 25( OH) D in men and women was 11. 38 ± 6. 29 ng / ml and9. 04 ± 5. 71 ng / ml,respectively. According to the IOF criteria of vitamin D,the ratio of serious deficiency,deficiency,insufficiency,and sufficiency was 62. 2%,28. 4%,6. 1%,and 3. 25%,respectively. 2) There was significant correlation between the levels of serum 25( OH) D and the season( r = 0. 228,P < 0. 05). 3) There was negative correlation between PTH and the level of serum 25( OH) D( r =- 0. 272,P < 0. 05). Conclusion Vitamin D insufficiency and deficiency exist in the adult population in Shanxi due to various factors. It should be paid widely attention and improved. More efforts should be done to reduce the incidence of vitamin D associated diseases.