鱼腥草氯仿部位的化学成分研究

Chemical constituents in chloroform fraction of Houttuynia cordata

运用色谱方法对鱼腥草氯仿部位的化学成分进行研究,并利用现代波谱技术对已分离得到的化合物进行结构鉴定。从中分离并鉴定了9个化合物,分别鉴定为:(S)-5,6,6a,7-四氢-2,10-二甲氧基-4H-二苯并[DE,G]喹啉-1,9-二醇(1)、(+)-isoboldineβ-N-oxide (2)、liriotulipiferine (3)、telitoxinone (4)、异波尔定碱(5)、(-)-clovane-2β,9α-diol (6)、苯甲酸(7)、acantrifoside E (8)、邻苯二甲酸二丁酯(9)。其中化合物2～9为首次从鱼腥草中分离得到,化合物1为新的阿朴菲类生物碱,命名为鱼腥草碱A。

Nine compounds were isolated from chloroform fraction of Houttuynia cordata,and the isolates were identified as follows:(S)-5,6,6 a,7-tetrahydro-2,10-dimethoxy-4 H-dibenzo[DE,G]quinoline-1,9-diol(1),(+)-isoboldineβ-N-oxide(2),liriotulipiferine(3),telitoxinone(4),isoboldine(5),(-)-clovane-2β,9α-diol(6),benzoic acid(7),acantrifoside E(8),and dibutyl phthalate(9).Among them,compound 1 was new,and compounds 2-9 were reported from this species for the first time.