中药质量常数用于牡丹皮饮片等级划分研究

Application of Chinese medicine quality constant in grades evaluation of Moutan Cortex

中药质量常数应用于中药饮片等级评价的文献报道日渐增多,中药质量常数综合、量化的优势尤为突出,中药质量常数评价成为饮片等级划分的一种新方法、新模式,学术界认可度较高。该文为确定中药质量常数建立牡丹皮饮片等级评价方法。从饮片企业收集15批牡丹皮饮片,分别测定外观性状指标和内在质量指标,计算其中药质量常数,并划分等级。得出牡丹皮饮片质量常数0. 016~0. 060,百分质量常数27. 4~100. 0。若把牡丹皮饮片划分成3等级,则:一等牡丹皮饮片质量常数≥0. 048,或百分质量常数≥80. 0%;二等牡丹皮饮片质量常数<0. 048且≥0. 030,或百分质量常数<80. 0%且≥50%;三等牡丹皮饮片质量常数<0. 030,或百分质量常数<50. 0%。该研究表明中药质量常数方法能客观地划分牡丹皮饮片等级,为其等级标准制定提供参考。通过结果也印证了牡丹皮饮片传统质量评价与质量常数评价具有一致性,并阐述了百分质量常数内涵。同时,建议尽快成立第三方中药饮片等级评价机构,统一饮片等级术语和为市场中药饮片企业提供等级制定服务。

There are more and more literature reports about the application of Chinese medicine quality constant in the grading evaluation of Chinese medicine decoction pieces.Chinese medicine quality constant has particularly prominent advantages in comprehensive quantification,so it has become a new method and mode for grading Chinese medicine decoction pieces,highly recognized by the academic circle.In order to determine the effect of Chinese medicine quality constant,a method of grades evaluation for Moutan cortex was established in this paper.15 batches of samples were collected from Chinese herbal slices enterprises to determine the external morphological indexes and inner quality indexes,calculate the Chinese medicine quality constant of Moutan cortex,and divide them into different grades.The results revealed that the range of the relative quality constant of these samples was from 0.016 to 0.060,with percentage quality constant from 27.4 to 100.0.If these samples were divided into three grades:the quality constant of the first grade should be≥0.048 or the percentage quality constant≥80.0;the quality constant of the second grade should be<0.048 but≥0.030 or percentage quality constant<80.0 and≥50.0;the quality constant of the third grade should be<0.030 or the percentage quality constant<50.0.This research indicated that Chinese quality constant can objectively divide grades of Moutan cortex decoction pieces,providing reference for formulating grades standards.It was also verified from the results that traditional quality evaluation of Moutan cortex was consistent with quality constant,and the connotation of percentage quality constant was elaborated as well.At the same time,it is suggested to establish a third-party Chinese medicine slices rating agency as soon as possible,which is to unify the terminology and provide rating services for the market.