我院门诊抗菌药物处方分析

Analysis of antibiotics prescription in outpatient department in our hospital

目的分析医院门诊处方中抗菌药物的使用情况,为临床合理用药提供参考。方法随机抽取医院2010年1月-2011年7月处方4300张,运用Excel电子表格对应用抗菌药物的处方进行统计、分析。结果 4300张处方中,应用抗菌药物处方1651张占38.4%。其中,抗菌药物联用处方611张占应用抗菌药物处方的37.0%;注射用抗菌药物处方206张,占抗菌药物处方的12.5%,口服抗菌药物处方1273张,占抗菌药物处方的77.1%。头孢菌素类和氟喹诺酮类药物应用频率较高,分别占33.2%、26.3%。儿科与内科应用抗菌药物频次较高,分别占32.9%、19.2%。抗菌药物不合理使用情况有无指征用药、药理作用拮抗及抗菌药物给药剂量不合理、抗菌药物配伍、抗菌药物使用时间间隔不合理等。结论医院门诊处方抗菌药物的应用存在诸多不合理情况,应进一步加强抗菌药物合理应用,提高我院临床用药的安全性、有效性、经济性。

Objective To analyze and evaluate the situation of using antibiotics in outpatient department,so as to provide references for rational drug use.Methods Randomly selected 4300 outpatient prescriptions.Used of excel spreadsheets,statistical analysed the prescriptions.Results In 4300 prescriptions,prescription of antimicrobials 1651 cases(38.4%).In which,combined with antibiotics prescription 611 cases,accounting for use of antimicrobials prescription 37.0%:Injectable antibiotic prescriptions accounted for 12.5% of prescription antibiotics,oral antibiotics prescribed antimicrobial drug prescriptions accounted for 77.1%.Cephalosporins and fluoroquinolones had a high frequency applications,accounting for 33.2%,26.3%.Pediatrics and miedical application of antimicrobial agents had a higher frequency,accounting for 32.9%,19.2%.The use of antimicrobial agents had no indication of drugs,pharmacological antagonists and improper administration of the program.Conclusion The utilization of antibiotics in outpatient department in our hospital is somewhat irrational,which thus need to further strengthen the rational use of antibiotics and improve the hospital ’ s clinical drugsafety,effectiveness and economy