血清降钙素原在早期诊断成年重症肺炎中的应用价值

Applied Value of PCT in Early Diagnosis of Adult Severe Pneumonia

目的探讨降钙素原在早期诊断重症肺炎的程度及预后的意义。方法搜集近两年来来我院治疗的48例重症肺炎的患者,与入院后的第1、3、5天分别对所有的患者进行降钙素原(PCT)和白细胞计数(WBC)检测,根据其预后情况将本组患者分为存活组和死亡组,对比两组患者的PCT和WBC的检测结果。结果死亡12例,存活36例;死亡组第3、5天及死亡前PCT的检测结果明显高于存活组(P【0.05);病情好转时,PCT水平下降;病情恶化时PCT明显升高。第1、3天对照WBC,无显著的统计学差异(P】0.05);死亡组第5天及死亡或者转出前的WBC水平明显高于存活组(P【0.05)。结论动态检测血清PCT的水平,还可以协助判断重症肺炎的预后。

Objective To discuss the significance of PCT in early diagnosis of degree and prognosis of severe pneumonia.Methods 48 cases of severe pneumonia were detected PCT and WBC 1、3、5 after being admitted into hospital and divided into survival group and death group according to prognosis.PCT and WBC results of both groups were compared.Results 12 cases died,36 survived.The PCT of death group on 3rd、5th day and before death were obviously higher than survival group(P < 0.05) ;PCT declined when condition improved and PCT rose when condition deteriorated.There was no significant difference between the PCT of 1st and 3rd day(P > 0.05) ;WBC of 5th day and after death of death group was obviously higher than survival group(P < 0.05).Conclusion Dynamic detection of PCT can help in estimate the prognosis of severe pneumonia.