吉西他滨联合奥沙利铂治疗耐药性晚期乳腺癌的护理体会

Nursing Experience of gemcitabine and oxaliplatin in the treatment of advanced breast cancer resistance

目的探讨耐药性晚期乳腺癌应用吉西他滨联合奥沙利铂治疗的临床护理。方法对我科2009年11月——2012年3月69例耐药性晚期乳腺癌患者,实施吉西他滨联合奥沙利铂治疗:第1和第8天给吉西他滨1000mg/m2静脉滴注,第2天给奥沙利铂针:100mg/m2静脉滴注,21天为一个疗程。化疗期间针对患者出现骨髓抑制、外周神经毒性、恶心及呕吐,皮疹等毒副作用,采取相应护理措施。结果 69例乳腺癌患者均完成了全程化疗,疗效好,副作用小。结论采取科学有效的护理措施,能满足患者对治疗的依从性,降低化疗并发症的发生率,提高患者维护自身健康的能力,延长患者的生命,提高生活质量。

Objective To investigate the resistance of advanced breast cancer application gemcitabine and oxaliplatin in the treatment of clinical care.Methods in our department from November 2009-2012 Mar.69 cases of drug resistance in patients with advanced breast cancer,the implementation of gemcitabine plus oxaliplatin treatment:1 and 8 days to gemcitabine 1000mg/m2 intravenous infusion,2 days to oxaliplatin needle:100mg/m2 intravenous infusion during chemotherapy for patients with bone marrow suppression,peripheral neurotoxicity,nausea and vomiting,skin rashes and other side effects,take the appropriate care measures.Results 69 patients with breast cancer to complete the full chemotherapy efficacy and side effects.Conclusion Scientific and effective care measures taken to meet the patients’ adherence to treatment,to reduce the incidence of complications of chemotherapy,improve the ability of patients to protect their own health and prolong the lives of patients,improve the quality of life.