脑胶质瘤MRI影像学表现之观察及探讨

Study on magnetic resonance imaging diagnosis of cerebral glioma

目的探讨脑胶质瘤的MRI影像表现的特点。方法回顾分析26例脑胶质瘤的MRI影像表现。结果脑胶质瘤的MRI的影像表现,低级别胶质瘤T1呈低信号,T2呈高信号;高级别胶质瘤T1、T2为混杂信号。脑胶质瘤的MRS的影像表现,肌酸(Cr)无明显变化;N-乙酰天门冬氨酸(NAA)下降,胆碱(Cho)增高,变化的程度由肿瘤的级别高低决定,高低级别的胶质瘤的肿瘤组织分别和对侧正常脑组织的NAA/Cr、NAA/Cho比值存在显着差异(P【0.01)。MR灌注图像上可见CBV较高的区域是肿瘤实质,同时相应区域的MTT延长,水肿带MTT略升高,CBV明显下降。PWI的CBV图像上,血供丰富的区域为复发的肿瘤组织,相比T1强化区域,对肿瘤实质定位更精确。结论脑胶质瘤的磁共振表现具有一定的特征性,结合磁共振波谱及磁共振灌注可明显提高其诊断正确率。

Objective Discussion on magnetic resonance imaging characteristics of cerebral gliomas.Methods Retrospective analysis of 26 cases of cerebral magnetic resonance imaging gliomas.Results MRI imaging of cerebral gliomas,low grade glioma low T1 signal,T2 high-signal;high Grade Gliomas of T1,T2 as mixed signals.Imaging of cerebral glioma of MRS,Creatine(Cr),no significant change;N-acetyl aspartate(NAA)decline;Choline(Cho)increased.The degree determined by the level of tumor,high and low levels of glioma tumors and contralateral normal brain tissue,respectively NAA/Cr and NAA/Cho ratio of significant difference(P<0.01).CBV a higher zone is visible on MR perfusion image tumors in real terms,at the same time extend the appropriate areas of the MTT,edema with MTT is slightly elevated,CBV dropped.PWI CBV images,blood supply a wealth of regional recurrence of tumor tissue,compared to the T1 zone,more accurate to the real location of tumors.Conclusion MRI manifestations of brain glioma have a certain feature,combined with MRS and PWI may significantly improve their diagnostic accuracy.