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阿奇霉素治疗儿童重症沙眼的疗程选择

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摘要 目的探讨阿奇霉素2日剂量是否能提高其治疗儿童重度沙眼的疗效。方法筛选重度沙眼的儿童患者50例,随机分成两组,所有患者均接受阿奇霉素20mg/kg/d,对照组给药1d,实验组给药2d,记录患者年龄、性别、沙眼状态,并采取拭子沙眼衣原体测定。对沙眼和感染随访6周。结果治疗前两组间年龄、性别、体重、沙眼浸润(Trachoma Intense,TI)患病率及PCR阳性率无显著性差异,治疗6周后,两组PCR阳性率明显低于治疗前(P【0.05),且实验组明显低于对照组(P【0.05),感染下降率明显高于对照组(P【0.05);治疗后两组TI发生率明显低于治疗前(P【0.05),但两组间无明显差异(P】0.05)。结论阿奇霉素2日剂量可有效控制儿童重度沙眼,在一定程度上起着防止沙眼衣原体感染复发的作用。
出处 《中国保健营养(下半月)》 2013年第3期825-825,共1页 China Health Care & Nutrition
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参考文献5

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