炎性因子与进展性卒中的关系

Relationship between inflammatory factor and stroke in progression

目的研究炎性因子与进展性卒中之间的关系,为进展性卒中的预测提供科学的依据。方法连续收集140例急性新发脑梗死患者,依据病情是否进展分为进展组(n=38)与非进展组(n=102)。检测两组患者各项生化指标,同时调查年龄、性别、吸烟、酗酒、糖尿病史等其他危险因素并进行单因素和多因素Logistic回归分析。结果单因素分析高血压病史、糖尿病史、PT、LDL、WBC、N%、CRP、PLT是进展性脑梗死的显著相关因素(P【0.05);Lo-gistic回归分析显示LDL、N%、CRP与卒中进展显著相关。结论炎性反应可能为脑梗死进展的危险因素。

Objective To study the relationship between inflammatory factors and stroke in progression,and provide scientific basis for the prediction of stroke in progression.Methods collected 140 cases of acute patients with cerebral infarction,according to whether the disease progressed into progressive group(n = 38) and non-progression group(n = 102).Two groups of patients with biochemical detection,at the same time,age,gender,smoking,drinking,history of diabetes and other risk factors for single and multiple factors Logistic regression analysis.Results The results of single factor analysis,history of hypertension,history of diabetes,PT,LDL,WBC,N%,CRP,PLT were significantly related with progressive cerebral infarction(P < 0.05) ;Logistic regression analysis showed that LDL,N%,CRP and stroke in progression was significantly related to.Conclusion The risk factors of inflammatory reaction may progress for cerebral infarction.